How cells do statistics? Inference, signal transduction and experimental design.
- Prelegent(ci)
- Michał Komorowski
- Afiliacja
- IPPT PAN
- Termin
- 23 stycznia 2013 10:30
- Pokój
- p. 5820
- Seminarium
- Seminarium „Biologia obliczeniowa i bioinformatyka”
Living cells are forced to solve inference problems as they
measure
constantly changing parameters of their environment. Cellular
biochemical machineries encode certain experimental
procedures, which, at least to some extent, must have been
evolutionary
optimised. Statistical methodology of optimal experimental
design,
therefore, can provide insight about information processing and
evolutionary adaptation of signal transduction networks. We
therefore explored the
analogy between inference and signal transduction to provide
potential design principles
of biochemical networks and informative experiments.