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Emergence of large densities in chemotaxis-growth systems
- Prelegent(ci)
- Prof. Michael Winkler
- Afiliacja
- Universitat Paderborn
- Termin
- 8 grudnia 2016 11:00
- Pokój
- p. 4060
- Seminarium
- Seminarium Zakładu Równań Fizyki Matematycznej
We consider variants of the Keller-Segel system of chemotaxis which contain logistic-type source terms and thereby
account for proliferation and death of cells. We briefly review results and open problems with regard to the fundamental
question whether solutions exist globally in time or blow up.
One focus will then be on the prototypical parabolic-elliptic system
\[
\begin{array}{l}
u_t=\varepsilon u_{xx} - (uv_x)_x + ru - \mu u^2,
0= v_{xx}-v+u,
\end{array} \right.
\]
in bounded real intervals. The corresponding Neumann initial-boundary value problem, though known to possess global bounded
solutions for any reasonably smooth initial data, is shown to have the property that the so-called
{\em carrying capacity} $\frac{r}{\mu}$ can be exceeded dynamically to an arbitrary extent during evolution in an
appropriate sense, provided that $\mu<1$ and that $\varepsilon>0$ is sufficiently small.
To achieve this, an analysis of the hyperbolic-elliptic problem obtained on taking $\varepsilon\to 0$ is carried out;
indeed, it turns out that the latter limit problem possesses some solutions which blow up in finite time
with respect to their spatial $L^\infty$ norm.\\
%
This result is in stark contrast to the case of the corresponding Fisher-type equation obtained
upon dropping the term $-(uv_x)_x$,
and hence reflects a drastic peculiarity of destabilizing action due to chemotactic cross-diffusion, observable
even in the simple spatially one-dimensional setting.
Numerical simulations underline the challenge in the analytical derivation of this result by indicating that
the phenomenon in question occurs at intermediate time scales only, and disappears in the large time asymptotics.\\
%
We thereafter briefly discuss extensions to multi-dimensional cases and fully parabolic systems.
account for proliferation and death of cells. We briefly review results and open problems with regard to the fundamental
question whether solutions exist globally in time or blow up.
One focus will then be on the prototypical parabolic-elliptic system
\[
\begin{array}{l}
u_t=\varepsilon u_{xx} - (uv_x)_x + ru - \mu u^2,
0= v_{xx}-v+u,
\end{array} \right.
\]
in bounded real intervals. The corresponding Neumann initial-boundary value problem, though known to possess global bounded
solutions for any reasonably smooth initial data, is shown to have the property that the so-called
{\em carrying capacity} $\frac{r}{\mu}$ can be exceeded dynamically to an arbitrary extent during evolution in an
appropriate sense, provided that $\mu<1$ and that $\varepsilon>0$ is sufficiently small.
To achieve this, an analysis of the hyperbolic-elliptic problem obtained on taking $\varepsilon\to 0$ is carried out;
indeed, it turns out that the latter limit problem possesses some solutions which blow up in finite time
with respect to their spatial $L^\infty$ norm.\\
%
This result is in stark contrast to the case of the corresponding Fisher-type equation obtained
upon dropping the term $-(uv_x)_x$,
and hence reflects a drastic peculiarity of destabilizing action due to chemotactic cross-diffusion, observable
even in the simple spatially one-dimensional setting.
Numerical simulations underline the challenge in the analytical derivation of this result by indicating that
the phenomenon in question occurs at intermediate time scales only, and disappears in the large time asymptotics.\\
%
We thereafter briefly discuss extensions to multi-dimensional cases and fully parabolic systems.
