A Calibrated Cellular Automata Model of in vitro Cultivated Multicellular Tumour Spheroids

Prelegent(ci)

Monika Joanna Piotrowska

Afiliacja

Uniwersytet Warszawski

Termin

10 października 2007 16:15

Pokój

p. 5840

Seminarium

Seminarium Zakładu Biomatematyki i Teorii Gier

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SEMINARIUM WSPÓLNE Z SEMINARIUM RTN. In this paper we present a quasi-two dmimensional Cellular Automata (CA)model describing the dynamics of the in vitro cultivated multicellular spheroid obtained from EMT6/Ro (mammary carcinoma) cell line. The CA model is coupled to the experimental data and shows extremely good agreement across a wide range of outputs including bulk growth kinetics, necrotic core formation and kinetics and response to environmental glucose levels.

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