Stability of periodic solution in a model of CAR-T cell immunotherapy

Speaker(s)

Marek Bodnar

Affiliation

MIM UW

Date

Oct. 11, 2023, 2:15 p.m.

Room

room 5070

Seminar

Seminar of Biomathematics and Game Theory Group

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I will talk about a model of CAR-T (Chimeric Antigen Receptor T) cell therapy that was presented in paper O. León-Triana et al.. (Cancers, 2021). I consider an system of 4 ODEs with impulses and continuous periodic function describing contiguous treatment. I prove existence of periodic, tumour-free, solution and study its stability. In particular I justify global convergence to this solution under suitable condition.

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