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Analysis of a mathematical model of solid tumor treated with CAR-T cells
- Speaker(s)
- Juan Belmonte Beitia
- Affiliation
- University of Castilla-La Mancha, Spain
- Date
- Jan. 19, 2022, 12:15 p.m.
- Information about the event
- 4060 oraz https://us02web.zoom.us/j/89788218933?pwd=aVc2UHdwRWMwZy8yK24rQTJWRW42QT09 Meeting ID: 897 8821 8933 Passcode: Biomat
- Seminar
- Seminar of Biomathematics and Game Theory Group
In this presentation, we address a theoretical study and its numerical simulations of CAR-T cell-based therapies for solid tumors. We study mathematically the periodic CAR-T cells instillations using impulsive differential equations which are studied using theory of dynamical systems. Thus, we calculate a critical value of the CAR-T cells dose for successful treatment.
Finally, we find a relationship between the number of doses and the strength of dose of treatment, which can be useful for medical applications.
